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CD8a-APC

E-AB-F1110E

CD3-PE CD4-FITC CD8a-APC

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E-AB-F1110E

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Alternate Names	CD8A, MAL, T-cell surface glycoprotein CD8 alpha chain, T-lymphocyte differentiation antigen T8/Leu-2
Cellular Localization	Membrane
Clone	OKT-8
Isotype	Mouse IgG2a, κ
Leadtime	咨询
Background	CD8a is a 32-34 kD type I glycoprotein. It forms a homodimer (CD8a/a) or heterodimer (CD8a/b) with CD8b. CD8, also known as T8 and Leu2, is a member of the immunoglobulin superfamily found on the majority of thymocytes, a subset of peripheral blood T cells, and NK cells (which express almost exclusively CD8a homodimers). CD8 acts as a co-receptor with MHC class I-restricted T cell receptors in antigen recognition and T cell activation and has been shown to play a role in thymic differentiation. Two domains in CD8a are important for function: the extracellular IgSF domain binds the α3 domain of MHC class I and the cytoplasmic CXCP motif binds the tyrosine kinase p56 Lck.
Abbre	CD8
Swissprot	P01732
Host	Mouse
Reactivity	Human
Clonality	Monoclonal
Isotype Control	APC Mouse IgG2a, κ Isotype Control[C1.18.4]
Applications	FCM
Research Areas	Immunology
Form	Liquid
Concentration	5 μL/Test
Conjugation	APC
Conjugation Information	APC is designed to be excited by the Red (627-640 nm) laser and detected using an optical filter centered near 660 nm (e.g., a 660/20 nm bandpass filter).
Spectrum
Storage Buffer	Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide.
Storage	This product can be stored at 2-8°C for 24 months. Please protected from prolonged exposure to light and do not freeze.
Expiration Date	24个月
Shipping	冰袋
Gene ID	925

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产品详情

Alternate Names	CD8A, MAL, T-cell surface glycoprotein CD8 alpha chain, T-lymphocyte differentiation antigen T8/Leu-2
Cellular Localization	Membrane
Clone	OKT-8
Isotype	Mouse IgG2a, κ
Leadtime	咨询
Background	CD8a is a 32-34 kD type I glycoprotein. It forms a homodimer (CD8a/a) or heterodimer (CD8a/b) with CD8b. CD8, also known as T8 and Leu2, is a member of the immunoglobulin superfamily found on the majority of thymocytes, a subset of peripheral blood T cells, and NK cells (which express almost exclusively CD8a homodimers). CD8 acts as a co-receptor with MHC class I-restricted T cell receptors in antigen recognition and T cell activation and has been shown to play a role in thymic differentiation. Two domains in CD8a are important for function: the extracellular IgSF domain binds the α3 domain of MHC class I and the cytoplasmic CXCP motif binds the tyrosine kinase p56 Lck.
Abbre	CD8
Swissprot	P01732
Host	Mouse
Reactivity	Human
Clonality	Monoclonal
Isotype Control	APC Mouse IgG2a, κ Isotype Control[C1.18.4]
Applications	FCM
Research Areas	Immunology
Form	Liquid
Concentration	5 μL/Test
Conjugation	APC
Conjugation Information	APC is designed to be excited by the Red (627-640 nm) laser and detected using an optical filter centered near 660 nm (e.g., a 660/20 nm bandpass filter).
Spectrum
Storage Buffer	Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide.
Storage	This product can be stored at 2-8°C for 24 months. Please protected from prolonged exposure to light and do not freeze.
Expiration Date	24个月
Shipping	冰袋
Gene ID	925